Can Cold Plunges Help Reduce Inflammatory Flares in MS?

Introduction

For people living with multiple sclerosis (MS), flare-ups—also called relapses or exacerbations—can be overwhelming. A flare might come on suddenly, with a wave of new or worsening symptoms like fatigue, muscle weakness, brain fog, or vision problems. These episodes are caused by bursts of inflammation that damage the myelin sheath—the protective coating around nerves in the central nervous system.

As more people turn to natural and complementary therapies for relief, cold plunges have captured attention as a promising tool for inflammation management. But can immersing yourself in cold water actually reduce inflammatory flares in MS? Let’s dive into the science, explore real-world applications, and look at how to use this therapy safely.

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🧠 Understanding MS and Inflammation

Multiple sclerosis is an autoimmune disease where the immune system mistakenly attacks healthy tissue in the central nervous system (CNS), particularly the myelin sheath. This damage disrupts nerve communication and leads to a wide range of symptoms.

🔥 What Causes MS Flares?

MS flares or relapses occur when:

  • The immune system becomes overactive
  • New lesions form on the brain or spinal cord
  • Environmental triggers (like stress, heat, illness) increase systemic inflammation

Cytokines—chemical messengers like IL-6, TNF-alpha, and IFN-gamma—play a major role in these inflammatory processes. When they’re elevated, so is the likelihood of a flare.

Reducing inflammation isn’t just about comfort—it’s a core part of MS management. This is where cold plunges may come in.

❄️ What Are Cold Plunges?

Cold plunges are a form of cold water immersion therapy where a person submerges part or all of their body in water typically between 10–15°C (50–59°F). Common methods include:

  • Ice baths
  • Cold plunge tubs
  • Outdoor winter swimming
  • Cryotherapy (less immersive but similar idea)

Cold plunging isn’t just for elite athletes anymore—people with chronic conditions are exploring its benefits for pain relief, inflammation control, immune modulation, and mood support.

🔬 The Science Behind Cold Plunges and Inflammation

1. Reduction in Pro-Inflammatory Cytokines

Research has shown that cold water immersion can significantly reduce levels of TNF-alpha and IL-6, two cytokines strongly linked to MS flares.

➡️ In one 2014 study, participants who practiced cold exposure alongside breathing exercises saw reduced inflammatory responses after being exposed to bacterial endotoxins (Wim Hof et al., PNAS, 2014).

2. Boost in Anti-Inflammatory Cytokines

Cold plunging doesn’t just suppress inflammation—it also increases anti-inflammatory cytokines like IL-10, which helps restore immune balance.

This balance is crucial for MS, where overactive immune responses can lead to neurological damage.

3. Vagus Nerve Stimulation

Cold exposure, especially to the face and neck, stimulates the vagus nerve—which controls the parasympathetic nervous system. Vagal activation is associated with:

  • Lower inflammation
  • Reduced stress hormone levels (like cortisol)
  • Better autonomic regulation in MS

This effect is called the cholinergic anti-inflammatory pathway—a natural way your body dials down inflammatory activity.

4. Hormetic Stress Response

Cold plunging is a form of hormetic stress—a mild challenge that encourages your body to adapt and grow stronger. Like exercise or fasting, short cold exposures may help:

  • Strengthen mitochondria
  • Improve resilience to stress
  • Enhance recovery after inflammation

📚 What Does Research Say About Cold Therapy and MS?

While research on cold plunges specifically for MS is still emerging, related studies offer encouraging signals:

A 2013 study in Frontiers in Bioscience noted that therapeutic hypothermia reduced CNS inflammation in neurodegenerative models.

A 2017 review of cold exposure and exercise recovery found consistent reductions in C-reactive protein (a key inflammation marker).

Anecdotally, MS communities report less fatigue, reduced swelling, and even fewer flares after consistent cold water use.

💡 Potential Benefits of Cold Plunges for MS Flares

Here’s how cold plunging may support MS management and potentially reduce flare frequency or severity:

Benefit How It Helps in MS
🔥 Lowers inflammation Reduces pro-inflammatory cytokines involved in flares
🧘Activates vagus nerve Promotes calm, immune balance, and autonomic regulation
🌬️ Enhances stress resilience Helps prevent stress-induced flares
🛡️ May protect brain tissue Cold has shown neuroprotective potential in animal studies
🌡️ Cools the body Counteracts heat-induced pseudo-flares

🧊 How to Safely Try Cold Plunges with MS

Cold therapy isn’t one-size-fits-all, especially with a condition like MS. Some people with MS have cold intolerance or experience spasticity when chilled. That’s why it’s essential to approach this slowly and mindfully.

🧊 How to Safely Try Cold Plunges with MS

Cold therapy isn’t one-size-fits-all, especially with a condition like MS. Some people with MS have cold intolerance or experience spasticity when chilled. That’s why it’s essential to approach this slowly and mindfully.

🧊 How to Safely Get Started with Cold Plunges for MS

Cold therapy can offer powerful benefits—but with MS, it’s important to be cautious. Some people experience cold sensitivity, muscle stiffness, or spasticity in response to lower temperatures. That’s why it’s essential to start gently, listen to your body, and progress at your own pace.

✅ Safe-Start Tips for People with MS

🔹 Begin with Face or Hand Immersion
Start by dipping your face into a bowl of cold water or soaking your hands in ice water for 30 seconds. This mild method stimulates the vagus nerve and initiates calming effects without full-body stress.

🔹 Try a Cold Shower Finish
At the end of your warm shower, gradually turn the temperature down for 30 to 60 seconds. Over time, work your way up to 2–3 minutes if comfortable.

🔹 Ease Into Short Cold Plunge Sessions
If using a cold plunge tub or ice bath, begin with just 30–60 seconds in water around 12–15°C (53–59°F). Always exit promptly and warm up afterward.

🔹 Monitor How You Feel
Keep a journal or log to track your symptoms, energy, and mood after each session. Are you feeling calmer? Clearer? Or more fatigued? Let your body guide your pace.

🔹 Avoid During Flares
Cold plunges are best used during stable periods. If you’re experiencing a relapse or active symptoms, consult your healthcare provider before starting.

🔹 Warm Up Intentionally
Always rewarm gently after a session. Wrap yourself in blankets, sip a warm drink, do light movement, or enjoy a heated space to bring your core temperature back up.

🧬 How Cold Exposure May Help Prevent Flares

Flares can be unpredictable, but we know certain triggers—like heat, stress, infection, and poor sleep—raise the risk. Cold plunging may:

  • Regulate autonomic function (balancing the sympathetic/parasympathetic nervous system)
  • Lower cortisol levels after an initial spike
  • Boost resilience to heat, which is known to worsen MS symptoms
  • Reduce overall inflammation, decreasing the likelihood of flares

Think of cold plunges as a tool that helps your body stay in regulatory mode, instead of overreactive mode.

🧠 Real Stories from the MS Community

Many people with MS are experimenting with cold plunges, cold showers, or cryotherapy as part of their self-care routines.

“I started plunging for 2 minutes a day, and it’s helped me stay clear-headed and more emotionally stable. I used to flare after stress—now it feels like my body bounces back quicker.” —Kate, 34, RRMS

“Cold water calms my nerve pain and helps me sleep better. I do it every morning now.” —James, 41, progressive MS

Of course, cold plunges are not a cure or a substitute for medication—but they can become part of a broader anti-inflammatory lifestyle.

⚠️ Who Should Be Cautious or Avoid Cold Plunges?

Cold therapy isn’t safe for everyone. You should speak to your doctor before trying it if you have:

  • Cardiovascular disease
  • Cold urticaria
  • Raynaud’s disease
  • Extreme cold intolerance
  • Ongoing infection or MS flare

Always listen to your body. If plunging triggers spasticity, pain, or fatigue, stop and reassess.

🧘 Combine Cold Plunges with Other Anti-Inflammatory Tools

For best results, cold therapy should be part of a holistic flare-prevention strategy, including:

  • 🧴 Vitamin D and Omega-3s
    Support immune balance and myelin protection
  • 🧘 Stress reduction techniques
    Breathwork, meditation, grounding exercises
  • 🥗 Anti-inflammatory diet
    Focus on leafy greens, berries, turmeric, fatty fish
  • 💤 Consistent sleep schedule
    Poor sleep increases inflammation and relapse risk
  • 🚶 Gentle movement
    Builds resilience without overstressing the system

Want supplements for people with MS? Click here.

💬 FAQs About Cold Plunges and MS

Q: Can cold plunges stop a flare that’s already started?
A: No, cold plunges won’t stop a full-blown flare. But they may help ease pseudo-flare symptoms triggered by heat, stress, or fatigue.

Q: What’s better—cold showers or ice baths?
A: Both have benefits. Showers are more accessible and easier to control. Plunges provide deeper vagus nerve stimulation and body-wide effects.

Q: How often should I do cold plunges for inflammation?
A: Start 2–3 times a week and see how your body responds. Some people work up to daily short sessions.

Q: Will it help if I’ve already had MS for years?
A: Possibly. Even if progression has begun, regulating inflammation can still improve quality of life and symptom control.

🔚 Final Thoughts: Chill Out to Turn Down the Fire

Cold plunges aren’t magic—but they tap into powerful physiological mechanisms that matter deeply for people with MS. By reducing inflammation, supporting nervous system regulation, and improving stress resilience, cold exposure may help you experience fewer flares, less symptom intensity, and more control over your wellness.

The key is consistency and listening to your body. If you’re curious, start with a 30-second cold shower tomorrow and see how you feel. Your nervous system might just thank you.

📌 TL;DR (Too Long; Didn’t Read)

  • MS flares are caused by spikes in inflammation and immune overactivity.
  • Cold plunges can lower inflammation, calm the nervous system, and stimulate healing.
  • Cold exposure may help reduce flare frequency and severity—but start slowly and safely.
  • Combine cold therapy with supplements, sleep, stress management, and gentle movement for best results.

📚 References

Kox, M. et al. (2014). Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. PNAS.

Peake, J. M. et al. (2017). Inflammatory responses to exercise and recovery. Frontiers in Physiology.

Rymaszewska, J., Ramsey, D., & Chładzińska-Kiejna, S. (2008). Cryotherapy in depression and anxiety. Archives of Psychiatry and Psychotherapy.

Mahbub, S. et al. (2021). Neuroimmune modulation through vagus nerve stimulation in autoimmune diseases. Journal of Neuroinflammation.

Shevchuk, N. (2008). Adapted cold showers as a potential treatment for depression. Medical Hypotheses.

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